Consider manifold-knot pair (Y, K) where Y is an integer homology sphere and K is a knot inside Y. In the joint work with Jen Hom and Matt Stoffregen, we proved that the minimum genus of a PL-surface bounded by K can be arbitrarily large in any bounding homology 4-ball. The proof uses Heegaard Floer homology. I will also talk about other related results.
Links:
[1] https://www.mpim-bonn.mpg.de/de/taxonomy/term/39
[2] https://www.mpim-bonn.mpg.de/de/node/3444
[3] https://www.mpim-bonn.mpg.de/de/node/12018