I'll steal ideas from Lickorish's proof that 3-manifolds bound 4-manifolds and Hatcher and Thurston's proof that the mapping class group of a surface is finitely presented to give, among other things, a new proof that $\Omega_4=\mathbb{Z}$ (using trisections where Lickorish uses Heegaard splittings). The key idea is that generic $n$-parameter families of functions on surfaces describe $(n+3)$-manifolds, at least for $n\leq 2$.
Links:
[1] https://www.mpim-bonn.mpg.de/taxonomy/term/39
[2] https://www.mpim-bonn.mpg.de/node/3444
[3] https://www.mpim-bonn.mpg.de/node/6656