The goal for this introductory talk is to motivate studying this question for smooth 4-manifolds.
Links:
[1] http://www.mpim-bonn.mpg.de/de/taxonomy/term/39
[2] http://www.mpim-bonn.mpg.de/de/node/3444
[3] http://www.mpim-bonn.mpg.de/de/TopologySeminar